John Holden Warren (August 23, 1825 – August 1, 1901) was an American medical doctor, Republican politician, and Wisconsin pioneer. He served two years in the Wisconsin State Senate representing Green County. In historical documents, his middle name is sometimes spelled "Halden".

Politically, Warren identified with the Whig Party and joined many other northern Whigs in the new Republican Party when it was established. On the Republican Party ticket, Warren was elected to the Wisconsin State Senate from Green County in 1857, serving in the 11th and 12th Wisconsin legislatures.[2] After leaving office, he served as chief clerk of the Senate for the next three terms.[3]